Organise everything that you want to pack in your bag or suitcase into designated piles. Start by packing towels, trousers, and tops in the bottom. Put the stuff that you will need to access easily on the top (jackets, shoes, etc.), as well as anything that might get damaged, creased or squashed.
Where possible compartmentalize your stuff into bags and containers to reduce damage from spillage or dirt. One tip I learnt last year is to roll your underwear and pack it into separate compartments in your suitcase/bag (see top left).
You can do this with the Eagle Creek Pack-It system: http://www.amazon.co.uk/Eagle-Creek-Pack-It-Tube-Pacific/dp/B002YIP89E/ref=wl_it_dp_o_pC_S_nC?ie=UTF8&colid=6QT9LQJEIZT2&coliid=IVJUSMH5E4G6B&psc=1
Love this jewellery organiser/roll: http://www.amazon.co.uk/Umbra-Little-Jewellery-Travel-Organiser/dp/B00A9SPC0G/ref=wl_it_dp_o_pC_nS_nC?ie=UTF8&colid=6QT9LQJEIZT2&coliid=I9U688G67A3FK
Carpe Diem xx